\usepackage {colortbl}
\begin{tabular}{lrr}
\large\textbf{Table title}\\[2mm]
\textbf{Description}
& \textbf{Column 1}
& \textbf{Column 2}\\[1mm]
Row one & mmmmmm & mmmmm \\
Row two & mmmmm & mmmm \\
Row three& mmmmmm & mmmmmm \\
Row four & mmmmmm & mmmmm \\
\cline{2-3}
Totals & mmmmmm & mmmmmm
\end{tabular}
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